Past symposia


Friday – 17.05.2024

15:00 Daphne Laan Ramirez Lab Connecting cytoskeletal organization to collective cilia dynamics in Paramecium


15:20 Lisa Fournier Fellay Lab Dissecting BRAF Inhibitor Resistance Landscapes: Identification of Distinctive 3′ UTR Shortening Patterns in Melanoma
15:40 PAUSE    
16:00 Jianhua Xing University of Pittsburgh From statistics to dynamics: emerging trend in data-driven single cell studies
16:45     Snacks and drinks

Friday – 26.04.2024 – Special PoLS Seminar – ROOM AI 1 153

15:00 Edo Kussell New York University Evolutionary phase transitions in fluctuating environments

Friday – 19.04.2024

15:00 Vitor Sudbrack UNIL Tandem repeat variation in partially selfing populations
15:20 Ilia Igashov Correia Lab Generative modeling for drug discovery
15:40 PAUSE    
16:00 Dave Moi UNIL Probing evolutionary relationships with structure
16:45     Snacks and drinks

Tuesday – 26.03.2024 – Special PoLS Seminar

14:15 Brian Hie Stanford University Biological foundation modeling from molecular to genome scale

Friday – 15.03.2024

15:00 Mariam Ait Oumelloul Fellay Lab  Genomic analysis of plasma metabolome in People Living with HIV
15:20 Benjamin Martin Suter Lab How dynamic is the dynamics of protein expression? Dynamics of adaption of protein decay to protein synthesis in mammalian cells
15:40 PAUSE    
16:00 Maksim Kholmatov   Predicting SF3B1 mutation status in single cell RNA-seq via cryptic splice site activation
16:20 FREE    
17:20     Snacks and drinks

Friday – 23.02.2024

15:00 Cyril Pulver Trono Lab Primate specific KRAB zinc finger proteins modulate cell cycle progression
15:20 Casper Goverde Correia Lab Functional design of soluble analogs of integral membrane proteins
15:40 PAUSE    
16:00 Anne-Marie Tassin I2BC Paramecium, a model to study cilia formation and ciliary movement
16:45 FREE    
17:30     Snacks and drinks

Friday – 19.01.2024

15:00 Luca Fusar Bassini La Manno Lab  Atlassing the lipidome of the adult mouse brain
15:20 Andreas Loukas Prescient Design Genentech Designing antibodies to target disease with generative AI: reporting from the trenches
16:05 PAUSE    
16:30 Marko Popovic Max Planck Institute Cell size heterogeneity controls tissue crystallisation in developing fruit fly wing
17:15     Snacks and drinks

Monday – 15.01.2024 – Special PoLS Seminar – ROOM ELA1

10:00 Rodrigo Reyes-Lamothe McGill University Tracking DNA-binding proteins, one at a time, to understand cells and their genome
11:00 Coralie Fumeaux CHUV Role of a conserved operon in cell wall homeostasis and antibiotic resistance in Pseudomonas aeruginosa


Friday – 08.12.2023

15:00 Fernando Meireles Dal Peraro Lab Investigating the evolutionary origins of B3 metallo-beta-lactamases and their mechanisms of membrane association
15:20 Albert Dominguez Mantes Weigert/La Manno Lab Spotipy: accurate and efficient spot detection for fluorescence microscopy
15:40 PAUSE    
16:00 Mikhail Tikhonov Washington University Emergent simplicity in microbial ecosystems
16:45 Daniel Pearce University of Geneva Defect driven morphogenesis, when does it pay to be active?
17:30     Snacks and drinks

Friday – 17.11.2023

15:00 Arthur Samurkas Dal Peraro Lab In-situ structure of fully palmitoylated SARS-CoV-2 virions
15:20 Sangwoo Kim Kim Lab How Mechanics Explains Solid-Fluid Transitions in Embryonic Tissues?
15:40 PAUSE    
16:00 Yi Jiang Georgia State University Leader, Follower, and Cheater in Collective Cancer Invasion
16:45     Snacks and drinks

Friday – 27.10.2023

15:00 Valeriia Timonina Fellay Lab HIV infection and Clonal Hematopoiesis synergistically affect all-cause mortality
15:20 Arne Schneuing Correia Lab Deep Generative Models: a New Paradigm for In Silico Drug Discovery
15:40 PAUSE    
16:00 Matthias Heinemann University of Groningen How a dynamic metabolism could control the eukaryotic cell cycle
16:45     Snacks and drinks

Friday – 22.09.2023

15:00 Ali Saadat Fellay Lab Host genomics of hepatitis E virus infection
15:20 Florian Schuder Yale University Development of smart DNA probes for multiplexed super-resolution microscopy
15:40 PAUSE    
16:00 Kirsty Wan University of Exeter   From sea cells to sea shells
16:40     Snacks and drinks

Wednesday – 06.09.2023 – Special PoLS Seminar

14:30 Mor Nitzan Hebrew University of Jerusalem Interpreting and manipulating layers of information in single-cell data

Tuesday – 20.06.2023 – Special PoLS Seminar (Room SV1717 et Zoom)

Zoom lien:

15:00 Pascal Notin (zoom only) Oxford University Hybrid protein language models for fitness prediction and design
16:00 Alex Hawkins-Hooker UCL Few-shot contrastive learning for protein interaction partner prediction

Friday – 16.06.2023

15:00 Samuel Bourgeat Jaksic/McCabe Labs Genetic and morphological basis of brain miniaturization in Drosophila melanogaster
15:20 Friso Douma Gönczy Lab Symmetry breaking and number control at the onset of centriole assembly
15:40 PAUSE    
16:00 Denis Mongin Université de Genève A dance of beats: quantifying heart rate dynamics and variability during effort with simple tools
16:45     Snacks and drinks

Friday – 26.05.2023

15:00 Sibo Wang Ramdya Lab Reverse-engineering Drosophila locomotor control through data-driven modeling
15:20 Alessandro De Simone UNIGE How does a regenerating scale reach its final size?
16:05 PAUSE    
16:30 Sara Mitri UNIL How do microbial species interact and how do we find out?
17:15     Snacks and drinks

Thursday – 25.05.2023 – Special PoLS Seminar

15:00 Matteo Degiacomi Durham University Protein structure, dynamics, and assembly through the lens of the computational microscope

Tuesday – 9.05.2023 – Special PoLS Seminar

15:00 Michael Laessig University of Cologne Real-time immune recognition

Friday – 21.04.2023

15:00 Riddha Manna Jaksic/Hess Labs Automated cobot-assisted high-throughput phenotyping of cognition in behaving Drosophila melanogaster
15:20 François Peaudecerf ETH and U. of Rennes Wall entrapment enhances bacterial chemotactic response to deposited aerosols in the microlayer
16:05 PAUSE    
16:30 Mark Chan San Francisco State University Physical limits to organelle growth and scaling in budding yeast
17:15     Snacks and drinks

Friday – 17.03.2023- Room AI.1.153

15:00 Davide Cois De Los Rios Lab Protein fibrils disassembly by the HSP70 chaperone machinery
15:20 Nicola Dietler Bitbol Lab  Disentangling phylogeny and optimization contributions in protein sequences
15:40 PAUSE    
16:00 Thomas Julou University of Basel Growth rate controls the sensitivity of gene regulatory circuits
16:45     Snacks and drinks

Friday – 24.02.2023

15:00 Olga Pushkareva Deplancke Lab Genome-wide evaluation of cis-regulatory coordination
15:20 Subham Choudhury Hatzimanikatis Lab Dynamical studies of Metabolism using Machine Learning
15:40 PAUSE    
16:00 Ercüment Cicek Bilkent University – Visiting professor at EPFL Detecting Copy Number Variants on Exome Sequencing Data via Deep Learning
16:45 Claude Loverdo CNRS-Sorbonne U Bacteria in the digestive tract : stochastic models of population dynamics, and interaction with the immune system
17:30     Snacks and drinks

Wednesday – 01.02.2023 – Special PoLS Seminar

14:00 Ned Wingreen Princeton University Why do biomolecular condensates ripen so slowly?

Friday – 20.01.2023

15:00 Halima Hannah Schede D’Angelo Lab A tool for the creation of lipidomic atlases: MAIA
15:20 Romane Mizeret Suter Lab The role of Nanog, Oct4 and Sox2 concentrations heterogeneity in regulating cellular identity
15:40 PAUSE    
16:00 Benjamin Towbin University of Bern Growth control from Cells to Organisms
16:45     Snacks and drinks


Friday – 16.12.2022

15:00 Ella Müller Gönczy Lab Deciphering mechanisms of symmetry breaking in C. elegans embryos
15:20 Benjamin Gallusser Weigert Lab Representation learning for live-cell imaging with permutation-equivariant time arrow prediction
15:40 PAUSE    
16:00 Guillaume Salbreux U. of Geneva Active surface flows and biological morphogenesis
16:45 Kurt Schmoller Helmholtz Institute of Functional Epigenetics Coordination of Protein and Organelle Homeostasis with Cell Size
17:30     Snacks and drinks

Friday – 18.11.2022

15:00 Yang Lin AQUA lab ZOOM – Real-time FLIM with on-FPGA RNN
15:20 Pernille Rainer Deplancke Lab A single-cell-based characterization of human white adipose tissues identifies an omentum-specific mesothelial-like stromal population that inhibits adipogenesis
15:40 PAUSE    
16:00 Raphaëlle Luisier IDIAP, Martigny Non-coding elements of mRNAs: a regulatory potential beyond their own transcripts
16:45 Clara Wong-Fannjiang UC Berkeley ZOOM – Conformal prediction for biomolecular design
17:30     Snacks and drinks

Friday – 28.10.2022 – Special PoLS Seminar – Room SV1717

15:00 Anatoly B. Kolomeisky Rice University When Will the Cancer Start?

Friday – 21.10.2022

15:00 Cristina Loureiro Casalderrey Oates Lab Using single-cell genomics to understand the transcriptional control of the Segmentation Clock
15:20 Laura Espinosa Montalban Salathé Lab ZOOM presentation – Public perception on vaccination and vaccination uptake in Brazil, 2013-2019
15:40 PAUSE    
16:00 Maria Romanova Michailidi U. of Geneva Morphogen gradient scaling by recycling of intracellular Dpp
16:45     Snacks and drinks

Friday – 16.09.2022

15:00 María A. Duque-Correa U. of Cambridge Caecaloids as a model to study host-whipworm interactions
15:40 PAUSE    
16:00 Guillermina Ramirez-SanJuan EPFL Cilia driven flows: Linking microscopic properties with emergent macroscopic dynamics
16:30 PAUSE    
16:45 Françoise Brochard-Wyart Institut Curie Micropipette aspiration of proteins coated bubbles: role of compressibility and porosity
17:15     Snacks and drinks

Friday – 20.05.2022

15:00 Zhidian Zhang Dal Peraro and Lashuel Lab The effect of post-translational modifications on intramolecular and intermolecular interactions
15:20 Vincenzo Caroprese PBL Lab Understanding the role of monomer-monomer interactions in the formation of crystalline surface patterns from trimeric DNA macromolecules
15:40 PAUSE    
16:00 Sim Sakong Suter Lab Target search dynamics of Sox transcription factors
16:20 Zhi Ming Xu Fellay Lab A genome-to-genome approach to study host-pathogen interactions

Friday – 22.04.2022

15:00 Cyril Pulver Trono Lab Statistical learning quantifies transposable element-mediated cis-regulation
15:20 Ilia Igashov Correia Lab Decoding Surface Fingerprints for Protein-Ligand Interactions
15:40 PAUSE    
16:00 Hugo Le Roy De Los Rios Lab Collective deformation modes promote fibrous self-assembly in protein-like particles
16:20 Anastasia Theodoropoulou Dal Peraro Lab Investigating the critical amino acids differentiating POU5F1B from its parent OCT4

Friday – 18.03.2022

15:00 Irene Lamberti Naef Lab From bulk to single-molecule: quantifying translation dynamics in mammalian cells
15:20 Alexis Arnaudon Blue Brain Project Frustrated oscillator dynamics with higher order interactions: theory and perspectives
15:40 PAUSE    
16:00 Mahdi Hijazi Barth Lab A Computational Study of Allosteric Signaling and Ligand Specificity in G-protein Coupled Receptors

Friday – 18.02.2022

15:00 Damiano Sgarbossa Bitbol Lab Comparing models for protein sequence generation
15:20 Alexandre Coudray Trono Lab Drug sensitivity inference at cell type level with predictive modeling
15:40 PAUSE    
16:00 Benjamin Martin Suter Lab The role of protein turnover in cell identity control
16:20 Casper Goverde Correia Lab Exploring the potential of deep learning in de novo protein design

Friday – 21.01.2022

15:00 Alex Lederer La Manno Lab Cell lipotype state transition estimation by lineage leaf-state Markov analysis
15:20 Jenny Sülzle Manley Lab Imaging self-assembly processes with label-free microscopy
15:40 PAUSE    
16:00 Chen Zhang Manley Lab Single-molecular imaging of bacterial peptidoglycan biosynthesis via D-amino acid derivatives


Friday – 17.12.2021

15:00 Willi Stepp Manley Lab Imaging dynamic biological events the smart way – Event-driven acquisition
15:20 Eunji Shin Trono Lab Transposable element expression contributes to the heterogeneity of colorectal cancer
15:40 PAUSE    
16:00 Vojislav Gligorovski Rahi Lab  
16:20 Freyr Sverrisson Correia Lab Prediction of protein interactions using geometric deep learning

Friday – 15.10.2021

15:00 Hana El-Samad UCSF Build to Understand: the Secret Lives of BioCircuits
16:00     Pause
16:15 Alexandra Shelest Lab De Los Rios Paper presentation: Spider silk self-assembly via modular liquid-liquid phase separation and nanofibrillation
16:30 Lorenzo Talamanca Lab Naef The philosophy of probability

Friday – 18.06.2021

15:00 Ece Ozelci Oates Lab Robustness to mechanical perturbations during zebrafish body axis morphogenesis

Friday – 21.05.2021

15:00 Navish Wadhwa Harvard University The bacterial flagellar engine has an automatic gearshift
15:30 Forrest Webler Andersen Lab Efficient data-driven model discovery in the era of big data

Friday – 16.04.2021

15:15 Sergey Ovchinnikov Harvard University A unified framework for understanding and evaluating generative models of protein sequences
16:15 Jan Skotheim Stanford University Towards molecular mechanisms linking cell growth and division

Friday – 19.03.2021

15:00 Pavan Ramdya Ramdya Lab Investigating latent representations of the world and self in the fly nervous system
15:20 Sofya Mikhaleva Persat Lab Finding structure in disorder: examining the central channel of the nuclear pore complex

Friday – 19.02.2021

15:00 Meritxell Saez The Francis Crick Institute Gene-free landscape models for development
15:30 Anne-Florence Bitbol Bitbol Lab Toward a universal model for spatially structured populations
15:45 Louis Dumas Barth Lab Uncovering and engineering the adhesion GPCR GAIN domain under force

Friday – 15.01.2021

15:00 Adam Gosztolai Ramdya Lab Unfolding the structure of real networks by multiscale dynamic geometry
15:15 Leo Scheller Correia Lab The bottom-up computational design of synthetic cell surface receptors
15:30 Zena Hadjivasiliou UNIGE Growth and patterning in development and evolution
16:00 Freyr Sverrisson Correia Lab Fast end-to-end learning on pro